| | Screen Play (Maygay, MV1 Video, ver. ?.?) (clone of: screenpl) | 1991 | Maygay | screenp4 | | 0.00 |
 | SD Gundam Psycho Salamander no Kyoui | 1991 | Banpresto / Bandai | sdgndmps | Shooter / Walking | 5.80 |
 | Sel Feena | 1991 | East Technology | selfeena | Maze | 4.20 |
 | Sengoku / Sengoku Denshou (NGH-017)(US) (clone of: sengoku) | 1991 | SNK | sengokuh | | 0.00 |
| Sengoku / Sengoku Denshou (NGM-017)(NGH-017) | 1991 | SNK | sengoku | Fighter / 2.5D | 6.67 |
![Sengoku Mahjong [BET] (Japan)](../snapsmall/MS_362.html) | Sengoku Mahjong [BET] (Japan) | 1991 | Sigma | sengokmj | Tabletop / Mahjong | 0.00 |
| | Skeet Shot | 1991 | Dynamo | skeetsht | | 0.00 |
| | Slugfest (L-1) | 1991 | Williams | sf_l1 | | 0.00 |
 | Soccer Brawl (NGH-031) (clone of: socbrawl) | 1991 | SNK | socbrawlh | | 0.00 |
| Soccer Brawl (NGM-031) | 1991 | SNK | socbrawl | Sports / Soccer | 7.78 |
 | Solitary Fighter (World) | 1991 | Taito Corporation Japan | solfigtr | Fighter / Versus | 6.40 |
 | Solvalou (Japan) | 1991 | Namco | solvalou | Shooter / Flying 1st Person | 6.00 |
 | Sonic The Hedgehog (Mega-Tech, set 1) | 1991 | Sega | mt_sonic | Platform / Run Jump Scrolling | 8.42 |
| Sonic The Hedgehog (Mega-Tech, set 2) (clone of: mt_sonic) | 1991 | Sega | mt_sonia | Platform / Run Jump Scrolling | 0.00 |
| | Special Criminal Investigation (Tourvision PCE bootleg) | 1991 | bootleg (Tourvision) / Taito | tvsci | | 0.00 |
| | Spider-Man vs The Kingpin (Mega-Tech) | 1991 | Marvel / Sega | mt_spman | | 0.00 |
| | Spider-Man: The Videogame (US) (clone of: spidman) | 1991 | Sega | spidmanu | | 0.00 |
| | Spider-Man: The Videogame (World) | 1991 | Sega | spidman | | 8.62 |
 | Starblade (Japan) | 1991 | Namco | starblad | Shooter / Command | 8.75 |
 | Steel Gunner 2 (Japan) (clone of: sgunner2) | 1991 | Namco | sgunner2j | | 0.00 |
